센터 구성
EM imaging
The Bio-EM Research Group is based at the Korea Basic Science Institute (KBSI) Ochang Center. As a national user facility,
we are equipped with Bio-High Voltage Electron Microscope (Bio-HVEM) facilities, providing electron microscopy imaging services to
researchers from both domestic and international backgrounds. Our team possesses extensive expertise and infrastructure in the
fields of biology, biochemistry, and medicine, enabling us to support various aspects of research, including sample preparation,
image acquisition, and data processing. Additionally, we offer educational and training programs to foster the growth of scientific knowledge.
At the heart of the Bio-EM Group lies the Bio-HVEM system, featuring an integrated sample preparation and transmission electronmicroscopy (TEM) visualization system. We offer comprehensive support for cryo-thin sectioning and immuno-EM analysis.
Moreover, our Bio-HVEM technology empowers us to conduct 3D investigations into the subcellular structures of cells and tissues through
electron tomography.
Our resources and analytical capabilities are dedicated to advancing research in the fields of neurobiology and cell biology, with a particular
focus on disorders of the degenerative brain.
In addition to our Bio-HVEM system, we boast advanced cryo-TEM instruments, such as the Talos Arctica G2 and Titan Krios, complete
with cutting-edge sample preparation equipment. These instruments allow us to provide structural analysis services for single particles and proteincomplexes.Furthermore, we offer training in related techniques.
Currently, we are utilizing these state-of-the-art instruments and technologies to delve into the three-dimensional structures of brain cell ion
channels and mitochondrial calcium uniporter protein complexes.